相关实验视频

Updated: Jul 28, 2025

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

Published on: January 5, 2017

维生素D可以改善刺激性肠综合征的症状:元分析

Chenxi Yan¹, Chenmin Hu¹, Xiaolong Chen¹

¹Pediatric Endoscopy Center and Department of Gastroenterology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, 3333 Bin Sheng Road, Hangzhou, 310052, Zhejiang, China.

|June 1, 2023

概括

维生素D补充剂可能有助于减少患有刺激性肠综合征 (IBS) 的患者的胃肠症状. 这次元分析发现,用维生素D对IBS症状严重性得分有显著的改善.

科学领域:

胃肠病学胃肠病学
营养科学营养科学
临床研究临床研究

背景情况:

刺激性肠综合征 (IBS) 影响全球5%-10%的人口,造成了相当大的负担.
新兴研究表明,维生素D补充剂可以缓解IBS症状,但有力的证据有限.

研究的目的:

在IBS患者中进行元分析,评估维生素D补充剂在控制胃肠道 (GI) 症状中的有效性.

主要方法:

在PubMed,Embase和Cochrane控制试验中央注册表中进行了系统的文献搜索,直到2022年3月.
六项随机对照试验 (RCT) 涉及572名患者被纳入了分析.
统计分析使用了加权平均差异 (WMD) 和95%置信区间 (CI),其显著性设置为P <0.05.

主要成果:

随着维生素D补充,IBS症状严重性得分显著降低 (WMD, -34.88; 95% CI, -62.48至 -7.27; P = 0.013).
在IBS生活质量得分中没有发现显著差异 (WMD, 3.33;95% CI, -5.12至 -11.77;P = 0.440).

结论:

维生素D补充剂显示出作为减少IBS患者胃肠道症状的有效干预措施的潜力.
进一步的研究可能是合理的,以探索其对生活质量的影响.

关键词:

IBS 症状严重程度症状严重程度刺激性肠综合征是什么意思进行元分析分析.生活质量生活的质量.维生素D 维生素D是一种维生素.

更多相关视频

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform

Published on: November 30, 2016

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation

Published on: July 27, 2022

相关概念视频

Irritable Bowel Syndrome I: Introduction

Irritable Bowel Syndrome I: Introduction

Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:

Irritable Bowel Syndrome III: Medical and Nursing Management

Irritable Bowel Syndrome III: Medical and Nursing Management

Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.

Drugs for Treatment of Diarrhea-Predominant IBS

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...

Chronic Bowel Disorders: Introduction

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...