相关实验视频

Updated: Aug 22, 2026

In Situ Detection of Bacteria within Paraffin-embedded Tissues Using a Digoxin-labeled DNA Probe Targeting 16S rRNA

In Situ Detection of Bacteria within Paraffin-embedded Tissues Using a Digoxin-labeled DNA Probe Targeting 16S rRNA

Published on: May 21, 2015

在牙周炎中新发现的病原体:来自关联和消除研究的证据

Eduardo Lobão Veras¹, Nídia Castro Dos Santos^1,2, João Gabriel S Souza^1,3

¹Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, SP, Brazil.

Journal of oral microbiology

|June 1, 2023

概括

这项研究发现了新的牙周病原体. 八种新型细菌物种显示出与牙周炎相关的强有力的证据,有助于了解其原因.

科学领域:

牙周病学牙周病学
微生物学微生物学
基因组学就是基因组学.

背景情况:

牙周炎的病因是复杂的,涉及口腔微生物组的转变.
识别新的牙周病原体对于了解疾病机制至关重要.

研究的目的:

评估新的牙周病原体的证据.
为了比较健康患者和牙周炎患者的新型细菌种群.
评估经过牙周治疗后的微生物变化.

主要方法:

协会研究对健康和牙周炎患者中的39种新物种进行比较.
消除研究评估微生物水平后的缩放和根植平整与或没有抗生素.
用于细菌量化而使用的棋盘DNA-DNA杂交.

主要成果:

八种新型细菌物种与牙周炎有着强烈的关联.
四种新型物种与牙周炎有中度的关联.
像兰斯菲尔德雷玛 (Lancefieldella rimae) 和克罗诺巴克特萨卡扎基 (Cronobacter sakazakii) 这样的特定物种受到严重影响.

结论:

强有力的证据支持Lancefieldella rimae,Cronobacter sakazakii,Pluralibacter gergoviae,Enterococcus faecalis,Eubacterium limosum,Filifactor alocis,Haemophilus influenzae和Staphylococcus warneri作为牙周病原体.
适度的证据支持大肠杆菌,Fusobacterium necrophorum,Spiroplasma ixodetis和金黄色葡萄球菌.
这些发现提高了对牙周炎病因的理解,并为未来的诊断和干预提供了信息.

关键词:

微生物群中的微生物群牙周病是指牙周病的发生.病因病因学病因学新的病原体的新病原体.口腔微生物学口腔微生物学牙周治疗牙周治疗

更多相关视频

Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells

Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells

Published on: December 17, 2015

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

相关概念视频

The Oral Microbiota

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...

Development of the Oral Microbiota

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...