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Updated: Jul 28, 2025

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
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在PLCZ1中的新突变导致早期胚胎停止作为男性因子

Yunying Lin1,2, Yi Huang1,2, Boyu Li1,2

  • 1Center for Reproductive Medicine Center, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Frontiers in cell and developmental biology
|June 1, 2023
PubMed
概括

在PLCZ1的双基突变导致男性不孕症和早期胚胎停产. 人工卵细胞激活和切割转移挽救了受精,并导致受影响患者的活产.

关键词:
ICSI与AOA一起进行了调查.在PLCZ1双基突变中.早期胚胎发育停滞 早期胚胎发育停滞男人的不孕不育症.多种精子多种性.

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