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沉浸后呼吸合规性的个体变化可能预测对沉浸肺胀的易感性
Olivier Castagna1,2, Arnaud Druelle3, Guillaume Michoud4
1Underwater Research Team - ERRSO, Military Biomedical Research Institute-IRBA, Toulon, France. castagna.olivier@gmail.com.
Sports medicine - open
|June 1, 2023
概括
潜水员有沉浸肺水腫 (IPE) 史,沉浸后肺功能变化更大,超声波肺彗星 (ULC) 更多. 这些发现表明,在沉浸期间测量肺部合规性可以帮助识别IPE风险较高的潜水员.
科学领域:
- 心血管和呼吸系统生理学
- 潜水医学是一门潜水医学.
- 肺部医学 肺部医学
背景情况:
- 浸泡性肺 (IPE) 是一种常见的潜水伤害,经常导致军用潜水员住院.
- 识别预测易受IPE影响的因素对于潜水员安全至关重要.
- 这项研究旨在确定与IPE风险相关的浸泡诱导的生理参数.
研究的目的:
- 为了确定水浸浸期间特定的生理变化,预测一个人的易患浸泡肺水腫 (IPE) 的可能性.
- 为了将这些生理变化与肺外血管水的存在相关联,IPE的标志物.
主要方法:
- 招募了18名经验丰富的男性潜水员,分为IPE (n=8) 和非IPE (n=10) 组,根据年龄,BMI和潜水历史进行匹配.
- 测量呼吸系统功能和呼吸系统合规性 (Crs) 在陆地上和头部出水浸泡期间.
- 在30分钟的羽翼游泳后评估超声波肺彗星 (ULC),以检测血管外肺水.
主要成果:
- 浸泡后降低的Crs与呼吸储备体积 (ERV),呼吸储备体积 (IRV) 和潮体积 (Vt) 的变化显著相关.
- ULC的数量与浸泡引起的通风功能变化 (ERV,IRV,Vt) 强烈相关,并减少了Crs.
- 具有IPE史的潜水员在ERV,IRV和Crs中表现出明显更大的变化,以及运动后更多的ULC.
结论:
- 个人对IPE的易感性各不相同,但通风功能的改变和ULC数量在统计上是相关的.
- 肺功能变化,特别是浸泡期间肺部遵守率降低,似乎可以识别IPE风险更高的潜水员.
- 测量这些浸泡诱导的肺功能变化可以作为IPE风险的预测测试.
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