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快速诊断测试价值和在低至中和高收入国家对抗菌药物管理的实施:混合方法审查

Luke S P Moore^1,2,3, Maria Virginia Villegas^4,5, Eric Wenzler⁶

¹Clinical Infection Department, Chelsea and Westminster NHS Foundation Trust, 369 Fulham Road, London, SW10 9NH, UK. l.moore@imperial.ac.uk.

Infectious diseases and therapy

|June 1, 2023

概括

快速诊断测试 (RDT) 在抗菌药物管理计划 (ASP) 中具有重要价值,但有效实施对于成功至关重要. 本研究提出了一个框架,在ASP中定义RTD的好处.

科学领域:

传染性疾病传染性疾病
临床微生物学临床微生物学
公共卫生公共卫生

背景情况:

快速诊断测试 (RDT) 已经成为患者治疗指导的先进方法.
在抗菌药物管理计划 (ASP) 中,R&DT的利用在全球范围内有所不同.
在ASP中RDTs的价值需要进一步定义,而不仅仅是个体患者的好处.

研究的目的:

评估RDTs在抗菌药物管理计划 (ASP) 中的价值.
建议在ASP中提供RDTs的价值框架,与每位患者的福利区分开来.
为在ASP中实施R&DT提供可操作的见解.

主要方法:

进行了一次文献综述.
来自不同国家的七名传染病专家小组 (哥伦比亚,日本,尼日利亚,泰国,英国,美国) 收集了这些见解.
基于专家的共识和文献证据,开发了一个价值框架.

主要成果:

在ASP中R&DT的利用在不同收入水平的国家之间是不一致的.
有效的实施被认为是实现ASP中的RTD价值的关键.
为选择适当的RDTs提出了可操作的建议.

结论:

研发开发技术对抗微生物药物管理计划具有重大潜在价值.
提出的价值框架可以帮助定义和衡量ASP中的RTD效益.
专家建议将RDTs纳入基本诊断清单和国家行动计划.

关键词:

抗微生物耐药性抗微生物耐药性抗微生物药物管理管理抗微生物药物管理计划.高,中,低收入国家.传染病的RDT和RDT是传染病.在护理场所进行检测.快速诊断测试是一种快速的诊断测试.

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