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Dijana Mayer1, Barbara Barun2,3, Karla Lazibat3
1Croatian Institute of Public Health, Zagreb, Croatia.
Acta neurologica Belgica
|June 1, 2023
概括
克罗地亚多发性硬化症 (pwMS) 患者的COVID-19疫苗接种率与一般人口相比,尽管总体而言不理想. 年龄特定的吸收率有所不同,年轻的pwMS接种疫苗更多,年长的pwMS接种疫苗少于一般人口中的同行.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经系统疾病.
- 接种COVID-19疫苗对弱势群体至关重要.
- 了解MS患者 (pwMS) 接种疫苗的情况对于公共卫生战略至关重要.
研究的目的:
- 为了比较PwMS和克罗地亚普通人口之间的COVID-19疫苗接种情况.
- 在pwMS中识别与接种疫苗相关的因素.
主要方法:
- 从MS Base注册表中检索 pwMS 的数据.
- 提取的人口和临床数据,包括DMT和疫苗接种情况.
- 从克罗地亚公共卫生研究所获得了一般人口疫苗接种数据.
主要成果:
- 总体而言,COVID-19疫苗接种率相似:pwMS中64.4%,一般人群中为66.3%.
- 年轻的pwMS (20-24岁) 比普通人群 (51.7%) 的吸收率 (74.1%) 高.
- 年龄较大的pwMS (65-69岁) 患者的吸收率 (33.3%) 比普通人群 (80.4%) 低.
- 接种疫苗的pwMS患者年龄较大,EDSS得分较高,疾病持续时间较长,疾病进展较快,并服用高效的DMT.
- 疾病持续时间较长是接种疫苗的积极预测因素.
结论:
- 克罗地亚的COVID-19疫苗接种率低于最佳水平.
- 在pwMS和普通人群之间,总体接种疫苗没有显著差异.
- 在pwMS人口中,可能需要针对特定年龄组和疾病特征制定有针对性的策略.
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