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合成,抗结核概况和分子对接研究,基于quinazolinone的皮里丁衍生物对抗耐药结核病

M S Raghu1, K Yogesh Kumar2, T Shamala3

  • 1Department of Chemistry, New Horizon College of Engineering, Bengaluru, India.

Journal of biomolecular structure & dynamics
|June 1, 2023
PubMed
概括

新的quinazolinone-pyridine化合物对对药物敏感和耐药的Mycobacterium结核病菌株表现出强大的抗菌活性. 化合物4e和4f表现出具有低毒性的有希望的抗结核作用,表明它们可能是MmpL3抑制剂.

关键词:
基纳佐利诺 (quinazolinone) 是一种可以细胞毒性 细胞毒性分子对接的分子对接.氨酸是什么?氨酸是什么?结核病是一种肺结核病.

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