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Updated: Jul 28, 2025

Uracil-DNA Glycosylase Assay by Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry Analysis
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对 uracil 损坏的 DNA 的灵活性进行系统评估

Paul B Orndorff1, Arjan van der Vaart1

  • 1Department of Chemistry, University of South Florida, Tampa, Florida, USA.

Journal of biomolecular structure & dynamics
|June 1, 2023
PubMed
概括

DNA的灵活性影响了 uracil DNA-glycosylase (UDG) 通过 uracil 的去除. 在 uracil 损伤附近具有特定基的 DNA 序列增强了灵活性,有助于 UDG 在基切割修复中的效率.

关键词:
造成的DNA损伤是DNA损伤.乌拉是一种酸盐.分子动力学分子动力学模拟模拟是指一个模拟模拟.乌拉 DNA 葡萄糖酶

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