第1部分:粘性菌:流行率,危险因素,临床特征和诊断
Joseph P Lynch1, Michael C Fishbein2, Fereidoun Abtin3
1Division of Pulmonary, Critical Care Medicine, Allergy, and Clinical Immunology, Department of Internal Medicine, The David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
菌病是一种严重的菌感染,主要影响免疫力低下的个体和失控糖尿病患者. 由于其迅速进展和高死亡率,及时诊断和治疗至关重要.
科学领域:
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 粘菌 (MCR) 是一种严重的感染,由Zygomycetes菌引起,特别是 Order Mucorales.
- 它是由子吸入,摄入或伤口接种引起的,主要影响发达国家的免疫力低下个体.
- 在发展中国家,MCR与不受控制的糖尿病和创伤有关,即使在免疫能力良好的人群中也是如此.
研究的目的:
- 审查粘膜菌的患病率,风险因素和临床表现.
- 强调迫切需要及时诊断和治疗MCR.
主要方法:
- 在PubMed进行了全面的文献搜索,截至2022年11月.
- 关键词包括:侵入性真菌感染,菌,粘菌菌,粘菌菌,粘菌菌,粘菌菌,粘菌菌,粘菌菌,菌,菌,菌,和诊断.
主要成果:
- 粘菌菌病的死亡率很高,在扩散的病例中超过90%.
- 感染迅速侵入血管,导致血栓形成和组织梗塞.
- 延迟治疗显著恶化了患者的结果.
结论:
- 粘性菌有六种形式,包括犀牛-轨道-大脑,肺和皮肤.
- 早期检测和干预对于改善MCR患者的生存率至关重要.
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