评估娱乐大麻合法化的物质使用结果,使用独特的共同双胞胎控制设计
J Megan Ross1, Hollis C Karoly2, Stephanie M Zellers3
1Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
The American journal of drug and alcohol abuse
|June 1, 2023
概括
娱乐大麻合法化 (RCL) 与大麻使用频率的增加有关,但没有更多的负面后果. 这项研究没有发现RCL州的酒精使用频率或酒精负面影响的差异.
科学领域:
- 公共卫生 公共卫生
- 药物使用研究研究 药物使用研究
- 成 药物 药物 药物 药物
背景情况:
- 越来越多的州制定了娱乐大麻合法化 (RCL).
- 需要了解RCL对各种物质使用行为的影响.
- 现有研究尚未完全阐明RCL对大麻和酒精使用模式和后果的细微影响.
研究的目的:
- 调查RCL对终身和过去一年使用大麻,酒精,烟草和其他药物的影响.
- 检查RCL后大麻,酒精和烟草使用频率的变化.
- 评估大麻与酒精和烟草的共同使用模式以及相关后果.
主要方法:
- 使用一个双胞胎对照设计,双胞胎对不一致,以生活在RCL状态.
- 样本包括3830名成年双胞胎 (41%男性),其中包括232对不一致的双胞胎.
- 使用简要大麻后果问卷和简要年轻成年酒精后果问卷评估酒精和大麻使用后果.
主要成果:
- 双胞胎在RCL状态显示较高的去年大麻使用 (OR=1.56) 和更频繁的大麻使用日 (β=0.47).
- 在大麻使用的负面后果中没有发现显著差异 (β=0.21).
- 在酒精使用频率上没有差异 (β=-0.05),但RCL状态 (β=-0.29) 的双胞胎报告了较少的负面酒精后果.
结论:
- 生活在娱乐大麻合法化州与大麻使用频率的增加有关.
- RCL似乎不会增加大麻使用的负面后果.
- 没有观察到RCL对饮酒频率或与酒精有关的负面后果的显著影响.
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