为什么某些椎间盘更容易发生退化? : 洞察到隔离的胸部"失能"的洞察力
Samuel Tin Yan Cheung1, Prudence Wing Hang Cheung, Jason Pui Yin Cheung
1Department of Orthopedics and Traumatology, The University of Hong Kong, Hong Kong SAR, China.
Spine
|June 1, 2023
概括
孤立胸部退行症是一种罕见的疾病,发生在生命的早期,并与特定的MRI发现有关. 双重胸脊椎退化表现出明显的成像特征,并与孤立的腰部问题不同地影响疼痛.
科学领域:
- 脊柱成像和退行性疾病
- 放射学和诊断成像 放射学和诊断成像
- 肌肉骨健康 肌肉骨健康
背景情况:
- 胸椎椎间盘很少受到磁盘退化 (DD) 的影响,这可能表明"退化"过程.
- 这些磁盘可能有先天的水分问题,在磁共振成像 (MRI) 上出现低强度.
- 了解胸部DD对于全面了解脊柱健康至关重要.
研究的目的:
- 用MRI来确定孤立胸部退行症的患病率.
- 识别相关的人口因素和特定的成像特征.
- 评估患者报告的受影响个体的生活质量结果.
主要方法:
- 对2007年志愿者进行了一项前性,基于人群的MRI研究.
- 盘变性被分级 (Pfirrmann/Schneiderman),并评估了,施莫尔节点 (SN),高强度区域 (HIZ) 和莫迪克变化等特征.
- 多变量后勤回归分析了成像研究结果与孤立胸部退行症之间的关联.
主要成果:
- 隔离胸部退行症在2.3%的队列中被发现,主要是女性 (61.4%),平均年龄为50岁.
- 相关因素包括较低的年龄,C6/7 HIZ,T8/9 HIZ和T8/9 SN.
- 双重胸椎变与L4/5后部凸起有关,并显示较高的身体疼痛和身体成分得分.
结论:
- 孤立胸部退行通常更早呈现,影响胸部中部区域,并与SN相关.
- 与隔离的腰椎退化相比,双重胸椎退化与较不严重的腰椎DD和腰部疼痛有关.
- 这些发现支持了影响胸部和腰部脊柱段的"失能"概念.
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