前皮层突触转录格局的成熟转变是精神分裂症相关的行为特征的基础:一种先天性大鼠模型

Marie Sønderstrup1, Mykhailo Y Batiuk2, Panagiotis Mantas3

  • 1Centre for Neuroscience and Stereology, Copenhagen University Hospital Bispebjerg-Frederiksberg, Denmark; Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Denmark.

概括

精神分裂症可能源于大脑发育受损. 这项研究揭示了大鼠模型中基因表达和突触成熟的改变,支持其用于理解精神分裂症的神经发育方面.

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