输血:表示情况,剂量,处方
Frank Bidar1,2, Stanislas Abrard1,3, Antoine Lamblin1
1Department of Anesthesiology and Critical Care Medicine, Hospices Civils de Lyon, Edouard Herriot Hospital, Lyon, France.
Contributions to nephrology
|June 1, 2023
概括
血液输血 (HP) 使用先进的吸附剂材料,但缺乏标准化的协议. 需要进一步的研究来确定HP疗法的有效临床应用的最佳时间,剂量和持续时间.
科学领域:
- 临界护理医学 临界护理医学
- 生物材料工程 生物材料工程
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 吸附剂材料具有先进的血 perfusion (HP) 技术.
- 目前的临床实践指南缺乏关于HP剂量和处方的共识.
- 标准化的协议对于确保HP的有效性至关重要.
研究的目的:
- 审查血 perfusion (HP) 疗法的当前状态.
- 为了突出HP中需要标准化的协议.
- 讨论HP设备的潜在应用和最佳操作条件.
主要方法:
- 对血液输液吸附剂材料近期进展的审查.
- 对有关HP处方和方式的当前临床实践的分析.
- 检查各种HP设备 (CytoSorb®,HA330/380,polymyxin B,Seraph®) 和它们的应用.
- 讨论血液流速,治疗时间和治疗频率.
主要成果:
- 血 perfusion (HP) 装置适用于败血症,但显示出肝功能衰竭,狂肠分裂,胰腺炎和其他危急情况的潜力.
- 惠普可以作为独立治疗或与脏替代疗法结合使用.
- 典型的血液流量范围在100-700毫升/分钟之间,不同设备的会话持续时间和重复协议各不相同.
- 目前的临床数据不足以确定HP的最佳操作条件.
结论:
- 血 perfusion (HP) 的最佳处方和模式对于有效性至关重要.
- 需要进一步的研究来确定HP治疗的最佳时间,剂量和持续时间.
- 确定最佳操作条件的研究将指导未来的血液输血临床应用.
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