年龄和临床生物化学参数对SARS-CoV-2感染临床严重性的影响

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Shariq Ahmad Wani¹, Babar Gulzar¹, Mosin Saleem Khan²

¹Department of Medicine, Government Medical College Srinagar and Associated Hospitals, Jammu and Kashmir, India.

Intervirology

|June 1, 2023

概括

低维生素D和甲状腺激素水平,以及老年和高血压,与严重的COVID-19有关. 这些因素可以帮助预测和管理冠状病毒疾病-2019 (COVID-19) 严重程度.

科学领域:

临床医学临床医学
内分泌学在内分泌学.
传染性疾病传染性疾病

背景情况:

由SARS-CoV-2引起的COVID-19大流行病已经在全球范围内压倒了医疗保健系统.
优先考虑治疗和减少医疗负担需要了解影响COVID-19临床严重性的因素.
这项研究调查了与印度克什米尔山谷COVID-19严重程度相关的临床生物化学参数.

研究的目的:

评估COVID-19的临床严重程度.
为了确定与COVID-19严重程度相关的临床生物化学参数.
帮助医疗保健工作者和政策制定者优先考虑COVID-19患者的治疗.

主要方法:

对236名感染SARS-CoV-2的个体进行了一项横截面研究.
通过实时聚合酶链反应 (RT-PCR) 确认了SARS-CoV-2感染.
血清中的葡萄糖,TSH和25-基维生素D水平使用光谱仪和CMIA测量.

主要成果:

总共分析了236名COVID-19患者,显示男性占主导地位 (72.9%).
观察到25-基维生素D缺乏的高患病率 (72.0%).
COVID-19的严重程度与年龄较大,高血压,低TSH和维生素D缺乏症显著相关.

结论:

高龄,高血压,低TSH和维生素D缺乏是COVID-19临床严重性的重要预测因素.
这些发现可以为COVID-19的临床管理和公共卫生策略提供信息.
了解这些生化标志物可能有助于减轻SARS-CoV-2感染的影响.

关键词:

25氧维生素D是25-氧维生素D的组成部分.ангиотензин转化酶 2 2 的作用.临床严重程度临床严重程度临床生物化学临床生物化学冠状病毒疾病-2019年查和克什米尔地区严重急性呼吸系统综合征冠状病毒2

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