对性结肠炎中的结直肠瘤进行内镜切除的有效性:一个多中心注册研究
Minami Hirai1, Shunichi Yanai1, Reiko Kunisaki2
1Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Yahaba, Japan.
Gastrointestinal endoscopy
|June 1, 2023
概括
在性结肠炎 (UC) 患者的结直肠瘤内镜切除 (ER) 显示出有希望的疗效和安全性. 虽然复发和超慢性病变需要监测,但ER与手术相比,提供了更好的整体存活率.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 结肠直肠手术 结肠直肠手术
背景情况:
- 性结肠炎 (UC) 患者面临着患结肠直肠癌的风险增加.
- 对于UC相关瘤的内镜切除 (ER) 的有效性和安全性尚未得到充分证实.
研究的目的:
- 评估结直肠瘤内镜切除 (ER) 的疗效和安全性,用于诊断为性结肠炎 (UC) 的患者.
主要方法:
- 追溯的,多中心的队列研究.
- 包括接受ER或结直肠瘤手术的UC患者 (2015年4月至2021年3月).
- 排除了先前有结直肠瘤病变的患者.
主要成果:
- 这次ER涉及238个病变 (142个EMR,96个ESD),穿孔率为2.5%.
- 在ER病变中,局部复发率为2.7%,甲时性瘤发生率为6.1%.
- 整体存活率在ER组与手术组相比显著更高 (P=.0085).
结论:
- 内镜切除 (ER) 似乎是UC患者选择性结直肠瘤的可接受治疗方法.
- 密切跟踪至关重要,以监测ER后的超慢性病变.
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