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迪奥斯基宁通过肝脏的FXR-SHP-SREBP1C/PPARα/CD36通路减轻非酒精性肝肥胖症

Suwen Chen1, Shangwen Sun2, Yanan Feng1

  • 1Shandong University of Traditional Chinese Medicine, Jinan, 250013, China.

European journal of pharmacology
|June 1, 2023
PubMed
概括

迪奥斯基宁 (DG) 通过调节脂质代谢,有效治疗非酒精性脂肪性肝病 (NAFLD). 这种天然化合物激活了Farnesoid X受体 (FXR) 途径,减少了肝脏中的脂肪积累.

关键词:
迪奥斯基因的存在法尔内索伊德X受体 (FXR) 是一种脂肪酸的吸收情况脂肪酸β-氧化 脂肪酸β-氧化非酒精性脂肪肝疾病 (NAFLD) 是一种非酒精性脂肪肝疾病.在新的脂质生成中.

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