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PHGDH通过Wnt/β-catenin通路促进食道状细胞癌的进展

Xiaoxuan Duan1, Yihuan Chen1, Kai Zhang1

  • 1Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan Province 450001, PR China.

Cellular signalling
|June 1, 2023
PubMed
概括

糖酸脱酶 (PHGDH) 在食道状细胞癌 (ESCC) 中高度表达,预测预后不佳. 通过抑制Wnt/β-catenin通路,PHGDH的 Knockdown抑制ESCC的进展,这表明PHGDH是潜在的治疗标.

关键词:
血管新生的产生.PHGDH PHGDH 的时间预测 预后 预测 预测核武器的扩散在Wnt/β-catenin中使用.

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