患有大血管封闭性中风,同时接受机械血栓切除和COVID-19的患者的结果:全国性的回顾性分析
Ian A Ramsay1, Hayes Fountain2, Turki Elarjani2
1Department of Neurosurgery, University of Miami Miller School of Medicine, Miami, Florida, USA ian.ramsay@med.miami.edu.
Journal of neurointerventional surgery
|June 1, 2023
概括
COVID-19显著恶化了患有大血管封闭 (LVO) 急性缺血性中风,接受机械血栓切除 (MT) 的患者的结果. 这些患者的死亡率更高,并发症更多,这凸显了COVID-19对中风治疗的影响.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 同时的COVID-19感染与经历大血管封闭 (LVO) 急性缺血性中风的患者的较差结果有关.
- 机械血栓切除术 (MT) 是LVO中风的关键干预措施.
研究的目的:
- 为了调查LVO中风患者的结果,这些患者同时接受机械血栓切除术 (MT) 和COVID-19感染.
- 为了比较LVO中风患者与COVID-19和没有COVID-19之间的结果.
主要方法:
- 2020年国家住院患者数据库 (NIS) 的分析.
- 包括急性缺血性中风和MT患者,按COVID-19状态分层.
- 后勤回归分析用于计算死亡率和并发症的几率比率 (OR),控制相关共变量.
主要成果:
- 虽然COVID-19患者年龄较小,但住院患者死亡率 (22.4% vs 10.1%) 和住院时间更长.
- 患有COVID-19的患者死亡几率增加 (OR2.78),例行出院几率降低 (OR0.65).
- 在COVID-19患者中观察到非神经学并发症的可能性更高,包括呼吸衰竭,肺栓塞,急性损伤和败血症.
结论:
- 同时的COVID-19感染与接受MT的LVO中风患者的更糟糕结果有关.
- COVID-19的非神经学并发症可能会导致观察到的不良结果.
- 研究结果强调了COVID-19对急性中风患者的管理和预后的重大影响.
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