相关实验视频

Updated: Jul 28, 2025

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

对甲状腺激素的敏感度指数与中国患者甲状腺结节的乳头甲状腺癌有关

Jie Sun^1,2, Jie Liu^1,2,3, Ting-Ting Wu^1,2

¹Department of Endocrinology, Endocrine and Metabolic Disease Medical Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

BMC endocrine disorders

|June 1, 2023

概括

甲状腺激素敏感度指数与患有甲状腺结节的中国患者的乳头甲状腺癌 (PTC) 风险有关. 中央敏感性与PTC有积极的关联,而外围敏感性显示出负面的关联.

科学领域:

内分泌学在内分泌学.
在瘤学瘤学.
甲状腺研究甲状腺研究

背景情况:

甲状腺激素敏感性和甲状腺癌之间的关系尚不清楚.
研究这种关联对于了解甲状腺结节的发展和癌症风险至关重要.

研究的目的:

探索甲状腺激素敏感度指数与乳头甲状腺癌 (PTC) 风险之间的联系.
为了评估中部和外围甲状腺激素敏感性,在中国患者甲状腺结节.

主要方法:

包括 1,998 个患有甲状腺结节的患者接受手术.
通过使用甲状腺刺激激素指数 (TSHI),TSH T4抵抗指数 (TT4RI),甲状腺反量基指数 (TFQI) 和参数甲状腺反量基指数 (PTFQI) 评估中心敏感性.
通过FT3对FT4比率评估了外围灵敏度,并使用后勤回归来分析与PTC风险的关联.

主要成果:

中心指数 (TSHI,TT4RI,TFQI,PTFQI) 显示出与PTC风险的积极关联.
更高的TSHI,TT4RI,TFQI和PTFQI与增加PTC的几率相关.
周边敏感性 (FT3/FT4比率) 与PTC风险有负相关性,较低的比率与减少的几率和较不先进的TNM分期有关.

结论:

甲状腺激素敏感度指数可能成为甲状腺结节患者PTC的新型预测指标.
需要进一步的研究来验证这些发现及其临床实用性.

关键词:

中部甲状腺激素敏感性敏感性乳头甲状腺癌是一种乳头甲状腺癌.周边甲状腺激素敏感性周边甲状腺激素敏感性预防预防预防在TNM中分阶段.

更多相关视频

A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images

A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images

Published on: April 21, 2023

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice

Published on: August 23, 2019

相关概念视频

Synthesis and Regulation of Thyroid Hormones

Synthesis and Regulation of Thyroid Hormones

Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...