流行病学因素和双胞胎儿童与对照者的眼睛表现的比较
Zhale Rajavi1,2,3, Hamideh Sabbaghi4,5, Reza Hasani6
1Negah Aref Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
BMC ophthalmology
|June 1, 2023
概括
与非双胞胎对照组相比,双胞胎儿童的折射误差,双眼盲和视率更高. 在双胞胎中早期查这些眼部疾病对于预防并发症至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 儿科 儿科 儿科
- 遗传学 遗传学 是一个
背景情况:
- 双胞胎研究为遗传和环境因素在疾病发展中的相互作用提供了独特的见解.
- 双胞胎的眼睛健康需要特别注意,因为潜在的共同遗传和子宫内影响.
研究的目的:
- 为了比较双胞胎儿童和年龄匹配的非双胞胎对照之间的流行病学和眼科发现.
- 确定在双胞胎群体中更为普遍的特定眼科疾病.
主要方法:
- 一项横截面研究比较了90名双胞胎 (180例) 与182名非双胞胎匹配儿童.
- 综合眼科检查,包括视敏度,折射和眼睛偏差的评估.
- 通过问卷收集的人口统计数据;双胞胎根据表型特征被分为单胞胎或双胞胎.
主要成果:
- 与非双胞胎相比,双胞胎的最佳校正视敏度 (BCVA) 显著降低,眼 (37.2% vs 10.4%) 和眼 (17.2% vs 1.6%) 的患病率更高.
- 双胞胎的球形折射误差更为高视;单胞胎双胞胎有更高的视和视率.
- 镜像双胞胎 (MIT) 表现出对称的眼睛特征,其中2.8%显示这种折射模式.
结论:
- 双胞胎有明显更高的视和视的发病率,特别是单胞胎双胞胎.
- 女性性别,较低的妊娠年龄和低出生体重等因素与双胞胎眼睛问题增加有关.
- 推对双胞胎儿童进行常规的视科查,以检查折射误差,眼盲和偏视,以减轻潜在的并发症.
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