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改善基于核酸的纳米材料稳定的方法

Xueping Xie¹, Wenjuan Ma², Yuxi Zhan²

¹Department of Stomatology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, P.R. China.

Current drug metabolism

|June 2, 2023

概括

基于核酸的纳米材料 (NAN) 在生物医学中表现有前途,但面临稳定性问题. 本综述探讨了用于更广泛应用的增强NAN稳定性的方法.

科学领域:

生物技术和纳米技术
材料科学材料科学材料科学
生物医学工程生物医学工程

背景情况:

基于核酸的纳米材料 (NAN) 是可编程,生物相容和非免疫原材料,通过基配对合成.
在生物医学应用中,NAN具有显著的潜力,例如药物输送和生物传感.
NANs的实际应用受其易于降解的敏感性限制.

结论:

提高NAN的稳定性对于释放它们在药物输送和诊断方面的全部潜力至关重要.
对稳定方法的持续研究将促进NAN从实验室转化为临床应用.
了解降解途径是设计更强大的基于核酸的纳米材料的关键.

关键词:

基于核酸的纳米材料离子度离子度离子度核酶降解的核酶降解稳定的稳定性稳定的稳定性

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