集中性缩几何形状是正常心脏结构和功能患者全球纵向应变受损的重要决定因素
Ryuichiro Anan1, Tatsuya Imoto2, Kumi Onizuka2
1Department of Cardiology, National Hospital Organization Miyakonojo Medical Center, 5033-1, Iwayoshi-cho, Miyakonojo, 885-0014, Japan.
Heliyon
|June 2, 2023
概括
集中性缩几何学显著损害全球纵向应变 (GLS),即使在心脏结构和功能正常的患者. 这一发现突出了影响心肌功能的关键因素,超出了像喷射分数这样的标准措施.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏机械学 心脏机械学
背景情况:
- 通过斑点追踪评估的全球纵向应变 (GLS) 是评估心肌功能的左心室喷射分数 (LVEF) 的可行替代方案.
- 在结构和功能上正常的个体中,GLS受损的决定因素仍然不清楚.
研究的目的:
- 确定导致正常心脏结构和功能患者GLS减少的因素.
- 调查左心室 (LV) 几何在GLS损伤中的作用.
主要方法:
- 评估了75名心脏结构和功能正常的患者,接受了非心脏手术.
- 评估患者特征,心脏生物标志物和心声回声学参数,包括LVEF,GLS,LV质量指数 (LVMI) 和相对壁厚 (RWT).
- 根据LV几何学对患者进行分类,并使用后勤回归来确定GLS受损的决定因素.
主要成果:
- 在32名患者中观察到GLS受损.
- 在正常和受损的GLS组之间注意到了RWT的显著差异.
- 确定LV集中性缩几何作为GLS受损的重要决定因素 (OR 22.4,P=0.042).
结论:
- 在其他健康个体中,与正常或奇特的过度缩小几何相比,集中式过度缩小几何与更受损的GLS有关.
- LV集中性缩几何学是正常心脏结构和功能的患者中GLS受损的显著预测因素.
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