相关实验视频
Updated: Jul 28, 2025

04:23
The Creation of a Rat Model for Osteosarcopenia via Ovariectomy
Published on: February 21, 2025
410
在接受血液透析的患者中,肉症和骨肉症
Ting Xiang1, Ping Fu1, Li Zhou1
1Division of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Frontiers in endocrinology
|June 2, 2023
概括
骨髓灰质疏松症 - - 骨髓灰质疏松症和骨质疏松症的组合 - - 在血液透析患者中显著增加死亡风险. 早期识别和管理对于改善这种脆弱人群的生存结果至关重要.
科学领域:
- 老年学是指老年学的学科.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 骨和矿物质的新陈代谢.
背景情况:
- 肉症和骨质疏松症是常见的,相互关联的疾病,与健康状况不佳有关.
- 同时诊断的骨质疏松症 (osteosarcopenia) 在血液透析 (HD) 患者中报告不足.
- 骨髓缩症对HD患者死亡率的影响尚不清楚.
研究的目的:
- 为了确定HD患者中肉类的患病率.
- 为了研究缩症和骨质疏松症之间的关联.
- 为了评估骨质缩症对HD患者生存风险的影响.
主要方法:
- 在约35个月的时间里,对209名成年HD患者的死亡率进行了随访.
- 评估了肌肉质量,手握强度和骨矿物质密度 (BMD).
- 使用考克斯回归分析来确定死亡风险因素.
主要成果:
- 麻症的患病率为37.3%,骨质麻症的患病率为22.3%.
- 骨髓缩症独立地与明显更高的全因死亡风险相关 (HR=3.74).
- 单独的肉症和单独的骨质疏松症都没有显示出与死亡率的显著关联.
结论:
- 患有HD的患者表现出高率的肉症和骨肉症.
- 肌肉质量和力量与BMD显著相关.
- 骨质疏松症是血液透析患者死亡的一个关键预测因素.
相关概念视频
Hemodialysis II: Procedure and Complications
43
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
43
Bone Disorders
3.7K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.7K
What is the Skeletal System?
53.0K
Overview
53.0K
Hemodialysis III: Nursing Management
52
The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this...
52
Chronic Kidney Disease II: Clinical Manifestations
46
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
46
Chronic Kidney Disease III: Interprofessional Care
51
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
51

