一个过程挖掘的临床指南合规的方法:在直肠癌的现实应用
Mariachiara Savino1, Giuditta Chiloiro2, Carlotta Masciocchi3
1Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Università Cattolica del Sacro Cuore, Rome, Italy.
Frontiers in oncology
|June 2, 2023
概括
使用伪工作流形式主义 (PWF) 的过程挖掘评估了欧洲医学瘤学会直肠癌指南的遵守. PWF确定了患者治疗偏差,突出了改善临床实践和资源优化的领域.
科学领域:
- 医疗信息学 医疗信息学
- 在瘤学瘤学.
- 过程采矿采矿采矿
背景情况:
- 临床指导方针旨在标准化癌症护理,但实际实践可能因患者和组织因素而异.
- 过程挖掘提供了一种方法,可以根据既定指南分析实际的处理途径.
研究的目的:
- 通过过程挖掘来评估遵守欧洲医学瘤学会 (ESMO) 的直肠癌治疗指南.
- 在现实世界患者队列中识别标准护理的偏差.
主要方法:
- 将ESMO直肠癌指南翻译成计算机可解释的伪工作流形式主义 (PWF).
- 从453名直肠癌患者的治疗数据中提取事件日志.
- 在pMineR库中使用PWF进行符合性检查和分析.
主要成果:
- 确定了接受延长治疗的直肠癌患者的一个子组.
- 偏差包括增加放射治疗剂量和在化疗期间添加氧沙.
- PWF促进了对准则的遵守和偏差的理解和解释.
结论:
- 伪工作流形式主义 (PWF) 是有效的评估临床指南在直肠癌的护理遵守.
- 过程挖掘可以确定特定的偏差,并告知多学科的治疗优化.
- 这种方法通过将指导方针建议与临床现实相结合,支持基于证据的医学.
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