食物组和泌尿癌风险:对前性研究的系统审查和元分析
Jingyi Qi1, Peng An1, Dekui Jin2
1Department of Nutrition and Health, Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, China.
Frontiers in nutrition
|June 2, 2023
概括
这项元分析发现,较高的水果,蔬菜,酒精,茶和咖啡摄入量可能会降低细胞癌和膀癌的风险. 相反,红肉摄入量与细胞癌的风险增加有关.
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 泌尿系统癌症是一个重大的全球健康问题.
- 饮食模式越来越被认为是各种癌症的可修改风险因素.
- 了解不同食物组在泌尿癌发展中的具体作用,对于预防策略至关重要.
研究的目的:
- 系统地评估12个食物组的摄入量与患尿道癌的风险之间的关联.
- 通过全面的元分析来综合现有证据.
主要方法:
- 在PubMed和Web of Science数据库中进行了系统的文献搜索,截至2023年4月1日.
- 七十三篇出版物被纳入了元分析.
- 使用随机效应模型计算总结风险比率 (RRs) 和95%置信区间 (95%CI).
主要成果:
- 增加水果 (100g/天),蔬菜 (100g/天),酒精 (12g/天) 和咖啡 (每天1杯) 的摄入量与细胞癌风险呈反向关联.
- 较高的红肉摄入量 (100克/天) 与细胞癌风险有关.
- 增加蛋 (50g/天) 和茶 (1杯/天) 的摄入量与膀癌风险相反相关.
结论:
- 这一元分析提供了证据支持水果,蔬菜,酒精,茶和咖啡对细胞癌和膀癌的保护作用.
- 需要进一步的研究来阐明各种食物组与尿道癌症发展之间的复杂关系,特别是对研究较少的食物组.
- 侧重于增加植物性食品的消费和减少红肉摄入量的饮食修改可能有助于预防泌尿癌.
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