产前大麻使用障碍对围产期结果的影响
Kristin C Prewitt1, Sarena Hayer, Bharti Garg
1From the Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR (KCP, SH, BG, AEB, ABC, JOL); and Department of Pediatrics, Oregon Health & Science University, Portland, OR (MAH).
Journal of addiction medicine
|June 2, 2023
概括
产前大麻使用障碍与更高的孕产妇并发症风险有关,如孕前和早产. 它还增加了新生儿问题的可能性,包括呼吸困难和婴儿死亡.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿健康 新生儿健康
- 公共卫生 公共卫生
背景情况:
- 由于立法变化和更广泛的社会接受,怀孕期间使用大麻的数量正在增加.
- 大麻仍然是孕妇中最常用的联邦非法药物.
- 了解与产前大麻使用障碍相关的围产期风险对于母亲和婴儿健康至关重要.
研究的目的:
- 评估产前大麻使用障碍和不良产周结局之间的关联.
- 量化与怀孕期间使用大麻相关的特定孕产妇和新生儿并发症的风险.
主要方法:
- 一项回顾性队列研究利用加利福尼亚州的相关医院出院和生命统计数据.
- 纳入标准:单独的,非异常分娩在妊娠年龄23至42周之间.
- 统计分析包括奇平方测试和多变量逻辑回归.
主要成果:
- 该研究包括2,380,446名患者,其中9,144名 (0.38%) 被确定为怀孕期间大麻使用者.
- 产前大麻使用障碍与妊娠高血压,孕前,早产和严重孕产妇发病率的风险显著增加有关.
- 与产前大麻使用障碍相关的新生儿结局包括呼吸应急综合征,对于妊娠年龄来说很小,NICU入院和婴儿死亡.
结论:
- 产前大麻使用障碍与增加的孕产妇和新生儿发病率和死亡率有关.
- 调查结果强调,需要提高有关怀孕期间大麻使用的意识和咨询.
- 该研究提供了证据,以指导怀孕前和产前护理策略,考虑到大麻使用率的上升.
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