医院住院的多病症老年人的中长期预后. 一个前性队列研究
Siena Molina1, Ana Martinez-Urrea1, Komal Malik1
1Multimorbidity Unit, Internal Medicine Service, University Hospital Mutua de Terrassa, University of Barcelona, Terrassa, Spain.
PloS one
|June 2, 2023
概括
住院后患有多种慢性疾病的老年患者的预后不佳,死亡率在七年内显著增加. 脆弱和身体依赖,而不是个别疾病,是生存的关键预测因素.
科学领域:
- 老年学和老年医学是老年学和老年医学.
- 内部医学 内部医学
- 公共卫生 公共卫生
背景情况:
- 医院住院后患有多种慢性疾病的老年患者的长期预后数据有限.
- 了解这种脆弱人群的生存轨迹对于医疗保健规划和患者管理至关重要.
研究的目的:
- 评估75岁以上多病症住院患者的中长期预后.
- 调查性别,年龄,虚弱,身体依赖和慢性疾病对七年死亡率的影响.
主要方法:
- 一项前性队列研究,包括至少有两种慢性疾病的75岁以上住院患者.
- 数据收集包括人口特征,慢性疾病 (查尔森并发症指数),临床脆弱度量表和巴特尔指数.
- 在7年的随访期内,分析了死亡率和生存预测因素.
主要成果:
- 一个由514名患者组成的队列 (平均年龄85岁) 显示出高死亡率,在7年内达到91%.
- 多变量分析确定了男性的性别,年龄,虚弱,身体依赖和并发症作为死亡率的重要预测因素.
- 集群分析揭示了三个不同的患者模式,具有显著不同的生存率.
结论:
- 在老年多病症患者中,单个慢性疾病的预后价值有限.
- 慢性疾病,虚弱和身体依赖的结合是这个人群生存的独立预测因素.
- 这些发现强调了超越个人诊断的整体评估对预测结果的重要性.
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