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Updated: Jul 28, 2025

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
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Published on: August 17, 2022

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协同的形状变化控制了甲基胺基基因组受体活性

Nathalie Lecat-Guillet1, Robert B Quast2, Hongkang Liu1,3

  • 1Institut de Génomique Fonctionnelle, Univ. Montpellier, CNRS, INSERM, 141 rue de la Cardonille, 34094, Montpellier Cedex 05, France.

Science advances
|June 2, 2023
PubMed
概括

阿洛斯特基调节剂通过控制甲基胺 (mGlu) 受体活性来微调神经递质作用. 这些配体稳定了mGlu2受体的完全活跃的二分体构成,这对大脑功能至关重要.

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