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Updated: Jul 28, 2025

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自然存在的人类开花化酶变体的生物化学特性

Rachel R Cueny1, Sameer Varma2,3, Kristina H Schmidt2

  • 1Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI, United States of America.

PloS one
|June 2, 2023
PubMed
概括

布鲁姆综合征酶 (BLM) 突变P868L和G1120R虽然不会引起布鲁姆综合征,但会增加基因组的不稳定性. 这些BLM变体保留了DNA结合和解功能,这表明体内效应驱动不稳定性.

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