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Updated: Jul 28, 2025

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9p21瘤抑制器位点的哈普洛缺陷导致骨髓微环境驱动的骨髓疾病

Jue Feng1, Pei-Feng Hsu1, Eduardo Esteva1

  • 1Department of Pathology, New York University Grossman School of Medicine, New York, NY.

Blood
|June 2, 2023
PubMed
概括

在小鼠中删除9p21位点会导致致命的骨髓质疏松症候群/骨髓扩散性新生瘤 (MDS/MPN) 类疾病. 骨髓流体突变驱动这种类似于MDS/MPN的疾病,影响骨形成和纤维化.

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