勃起器脊柱肌肉的厚度与肺结核患者的死亡率之间的关系
Masafumi Shimoda1, Takashi Yoshiyama1, Yoshiaki Tanaka1
1Respiratory Disease Center, Fukujuji Hospital, Japan Anti-Tuberculosis Association (JATA), Kiyose City, Tokyo, Japan.
Respiratory investigation
|June 2, 2023
概括
勃起器脊柱肌肉厚度 (ESMT) 和横截面积 (ESMCSA) 是结核病患者死亡率的强有力的预测因素. 用ESMT和ESMCSA测量较低的肌肉质量表明死亡风险更高.
科学领域:
- 老年病的医生 老年病的医生
- 肺部病理学 肺部病理学
- 放射学 放射学是一门学科.
背景情况:
- 骨肌肉质量是已知的老年人死亡率预测指标.
- 骨肌肉质量与结核病结局之间的关系尚不清楚.
- 勃起脊柱肌的截面面积 (ESMCSA) 和勃起脊柱肌的厚度 (ESMT) 是骨肌肉质量的测量.
研究的目的:
- 调查ESMT,ESMCSA和结核病患者死亡率之间的关系.
- 确定ESMT或ESMCSA是否是该人群死亡率的独立预测因素.
主要方法:
- 从267名较老的结核病患者 (≥65岁) 进行了回顾性数据收集.
- 患者被分为60天死亡率组 (n=40) 和60天生存率组 (n=227).
- 测量和比较ESMT和ESMCSA;使用多变量Cox比例危险模型.
主要成果:
- ESMT显示与ESMCSA有很强的相关性 (r=0.991,p<0.001).
- 与生存组相比,ESMCSA和ESMT的死亡率在死亡组显着较低 (两者p<0.001).
- 多变量分析显示ESMT (HR 0.870,p=0.003) 和ESMCSA (HR 0.998,p=0.009) 是60天死亡率的独立预测因素.
结论:
- 在ESMCSA和ESMT之间存在强烈的相关性.
- 无论是ESMT还是ESMCSA都是结核病患者死亡的重要风险因素.
- 与ESMCSA相比,ESMT提供了一种更简单,更有效的方法来预测死亡率.
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