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Updated: Jul 28, 2025

Evaluation of Caspase Activation to Assess Innate Immune Cell Death
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在对血红蛋白和PAMP的反应中,NLRP12-PANoptosome激活了PANoptosis和病理学

Balamurugan Sundaram1, Nagakannan Pandian1, Raghvendra Mall1

  • 1Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Cell
|June 2, 2023
PubMed
概括

NLRP12是一种细胞体传感器,可触发炎症和PANoptosome的激活,从而导致细胞死亡和炎症. 删除NLRP12受保护的小鼠,突出其在血液溶解疾病中的作用.

关键词:
在 DAMP一个 IRF1在NLRP12在 PAMP在RIPK在TLR2在TLR4细胞亡类植物卡斯帕斯-1卡斯帕斯-8气体皮质血红素血液溶解炎症组炎症性细胞死亡尸体死亡热症

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