相关实验视频
Updated: Jul 28, 2025

Contrast Enhanced Vessel Imaging using MicroCT
Published on: January 27, 2011
双对比光子计数微型CT使用和一种新的基对比剂
Carlo Amato1,2, Markus Susenburger1,3, Samuel Lehr1,3
1Division of X-Ray Imaging and Computed Tomography, German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany.
一种新的木纳米粒子对比剂显示了长时间的循环和对临床前成像的卓越增强. 一个新的多对比协议使心脏结构和血管系统的同时成像成为可能.
科学领域:
- 医疗成像医学成像
- 纳米技术 纳米技术
- 材料科学 材料科学 材料科学
背景情况:
- 临床前成像需要先进的对比剂来增强可视化.
- 石纳米粒子由于其高原子数而具有作为新型对比剂的潜力.
- 开发多对比协议可以提高诊断能力.
研究的目的:
- 在体内描述一种新的基于木的纳米粒子对比剂.
- 设计和测试用于心脏应用的多对比成像协议.
- 为了比较微型计算机断层扫描的和对比剂.
主要方法:
- 微计算机断层扫描仪与光子计数探测器的组装.
- 在体内给小鼠服用木纳米颗粒,并连续扫描5小时.
- 开发和测试使用光谱数据进行材料分解的多对比剂协议.
主要成果:
- 石纳米颗粒证明了最高血管增强1100HU,半衰期约为260分钟.
- 在注射后5小时内,在肝脏,脏和肠壁中观察到显著的积累.
- 幻影研究表明,比斯木在各种管电压上提供比更大的对比增强.
结论:
- 这种新型比斯木特剂具有很长的循环时间,适合临床前研究,与剂相比,它提供了更好的对比度.
- 开发的多对比方案对心脏结构,血管和棕色脂肪组织的同时成像是有效的.
- 该剂在肠壁中的增强表明了未来腹部和瘤成像协议的潜力.
更多相关视频
08:13In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
08:41Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
相关概念视频
Radiological Investigation I: X-ray and CT
Phase Contrast and Differential Interference Contrast Microscopy
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Imaging Studies III: Computed Tomography
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET