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Updated: Jul 28, 2025

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
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Published on: March 24, 2023

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在非酒精性脂肪肝疾病中识别底层膜基因和相关的分子亚型

Zhaoxiang Wang1, Huijuan Qin1, Qichao Yang2

  • 1Department of Endocrinology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
|June 2, 2023
PubMed
概括

这项研究确定了与非酒精性脂肪性肝病 (NAFLD) 进展相关的底层膜基因. 这些发现揭示了新的生物标志物,并突出了NASH异质性,以改善诊断和治疗.

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相关概念视频

Cell Specific Gene Expression01:58

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
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Type IV Collagen of Basal Lamina01:05

Type IV Collagen of Basal Lamina

Type IV collagen is a 400 nm long, network-forming collagen that acts as a barrier between the epithelial and endothelial cells. Type IV collagen  forms the backbone of the basement membrane by scaffolding with laminin, entactin, proteoglycans, and fibronectin. Apart from rendering structural support to the basement membrane, it also helps entail signaling potentials necessary for both pathological and physiological functions.
A type IV collagen molecule has six alpha chains which can...
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