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带有先天性腹膜的先天性心脏病:手术决策和结果

Latoya A Stewart¹, Rebecca R Hernan², Christopher Mardy³

¹Columbia University Vagelos College of Physicians and Surgeons, New York, NY.

The Journal of pediatrics

|June 2, 2023

概括

先天性心脏病 (CHD) 影响了19%的先天性隔膜 (CDH) 患者. 这两种情况的手术修复都会导致很好的生存率,指导未来的治疗和咨询.

科学领域:

儿童心脏病学儿童心脏病学
生产性心脏手术手术生产心脏手术
新生儿医学新生儿医学

背景情况:

kongenital diaphragmatic hernia (CDH) 是一种严重的疾病,通常与先天性心脏病 (CHD) 相关.
了解CDH患者的CHD谱对于手术决策和预后至关重要.
结果可以根据心脏病和相关异常的复杂性而有很大差异.

研究的目的:

在CDH患者队列中描述CHD的类型.
评估手术策略和结果与心脏病复杂性和并发症有关的情况.
为受CDH和CHD影响的家庭提供产前和产后咨询信息.

主要方法:

在2005年1月1日至2021年7月31日期间被诊断患有CHD和CDH的患者的回顾性审查.
用于诊断的心声回声图数据.
队列被分为存活和非存活组在释放时进行比较分析.

主要成果:

临床显著的CHD在19%的CDH患者中存在.
在接受CHD和CDH同时修复的新生儿中,存活率很高 (90%).
不幸存者更经常患有未修复的CDH (69%) 和CHD (88%),表明手术决定影响结果.

结论:

在新生儿中同时手术修复CHD和CDH,可以获得很好的生存率.
患有单胞体生理学的患者的生存率很低,需要仔细的咨询.
复杂的病变,如大动脉的转移,在及时干预的情况下具有有利的结果.

关键词:

心脏和胸部外科手术遗传学遗传学遗传学是一个结果就是结果.产前咨询咨询产前咨询

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