持续有机污染物对缺血性中风和所有中风患者的影响:系统性审查和元分析
Priya Dev1, Kamalesh Chakravarty2, Manoj Pandey3
1Department of Neurology, Institute of Medical Science, Banaras Hindu University, Varanasi 221005, India.
Toxicology
|June 2, 2023
概括
像持久性有机污染物 (POP) 这样的环境污染物显示出与缺血性中风风险相关的趋势. 居住在POP来源附近可能会增加暴露和中风风险,需要进一步调查.
科学领域:
- 环境健康 环境健康
- 神经学 神经学
- 毒理学 毒理学 毒理学
背景情况:
- 环境污染物和中风之间的联系仍然不清楚,对空气,噪音和水污染的发现不一致.
- 持久性有机污染物 (POP) 是一类环境污染物,其与缺血性中风的关联需要进一步阐明.
研究的目的:
- 系统地审查和元分析持久性有机污染物 (POP) 和缺血性中风之间的关联.
- 评估与生活在POP污染源附近的暴露相关的缺血性中风风险.
主要方法:
- 截至2021年6月30日,在多个数据库中进行了全面的文献搜索.
- 在使用纽卡斯尔-太华规模进行质量评估后,包括了五项符合条件的研究.
- 系统性审查和元分析被用来综合发现.
主要成果:
- 聚二 (PCB) 是与缺血性中风有关的最常被研究的POP,显示出与中风相关的趋势.
- 居住在POPs污染地点附近被确定为增加暴露和增加缺血性中风风险的风险因素.
结论:
- 这次审查表明,POP暴露和缺血性中风之间存在潜在的积极关联.
- 需要进一步进行广泛的研究,才能确定POPs和缺血性中风之间的因果关系.
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