潜在的应用的Atractylodes大脑科伊兹. 作为一种用于骨质调节的天然药物:一篇评论
Yikang Yu1, Danqing Fu2, Hengpu Zhou1
1School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Journal of ethnopharmacology
|June 2, 2023
概括
吸引类巨头科伊兹科伊兹. (AM) 根提取物通过刺激骨质生成和抑制骨质结晶生成来促进骨生长. 这种传统中医药为调节骨质量和改善骨健康提供了潜在的机制.
科学领域:
- 药理学 药理学是指药理学的学科.
- 骨生物学 骨生物学 骨生物学
- 传统中国医药 传统中国医药
背景情况:
- 吸引类巨头科伊兹科伊兹. (AM) 根在中国传统医学中有着悠久的历史.
- AM提取物具有多样化的药理作用,包括抗炎,抗氧化和免疫调节性质.
- 最近的研究强调了AM在调节骨质中的潜力,需要阐明机制.
研究的目的:
- 审查 AM 调节骨质的已知和潜在机制.
- 探索参与AM对骨影响的分子途径.
- 提供关于AM在骨质调节中的未来研究方向的观点.
主要方法:
- 在多个数据库 (Cochrane,Medline,Embase等) 中进行全面的文献搜索. 在2023年1月1日之前.
- 包括专注于Atractylodes macrocephala Koidz.的研究在内的研究. 根提取物及其作用.根提取物及其作用.
- 综合与活性物质,标和途径相关的发现.
主要成果:
- 在AM根中发现了119种天然活性物质.
- 探索了骨生长的潜在目标和途径,包括,Wnt/β-catenin和BMP/Smads途径.
- 介绍了关于AM在骨质调节中的未来研究的见解.
结论:
- 亚美根提取物促进骨质生成 (骨形成) 并抑制骨质结晶形成 (骨再吸收).
- 这些影响有助于改善营养吸收,肠道健康,内分泌功能和免疫反应.
- 通过多种机制,AM显示出增强骨健康的巨大潜力.
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