使用光滑混合模型的孕产妇体重潜伏轨迹和与不良妊娠结果的关联
Shirin Faraji Azad1, Akbar Biglarian2, Maryam Rostami3
1Department of Biostatistics and Epidemiology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
确定怀孕期间母亲体重轨迹对于预测不良结果至关重要. 遵循低体重轨迹的女性面临着显著更高的风险,例如早产和新生儿并发症,这凸显了适当体重增加的重要性.
科学领域:
- 健康 数据科学 数据科学
- 纵向数据分析 纵向数据分析
- 怀孕的结果 怀孕结果
背景情况:
- 在健康数据科学中,类成员对于理解人口异质性至关重要.
- 母体体重的纵向轨迹与怀孕结果有关.
- 统计模型用于识别不同的参与者群体.
研究的目的:
- 使用光滑混合模型 (SMM) 识别母亲体重的潜纵轨迹.
- 检查已识别的孕产妇体重轨迹与不良妊娠结果之间的关联.
- 提供对最佳孕产妇体重增加的见解,以尽量减少风险.
主要方法:
- 利用了877名孕妇的数据,参加了胡泽斯坦维生素D缺乏症查计划.
- 应用了光滑混合模型 (SMM) 来分类母体体重轨迹.
- 使用后勤回归来分析轨迹与不良妊娠终点之间的关联.
主要成果:
- 确定了三个不同的潜伏孕产妇体重轨迹:低,中,高.
- 与中等轨迹相比,低体重轨迹 (轨迹1) 显示出子,早产,NICU入院和复合新生儿事件的风险明显更高.
- 在孕产妇体重增加和孕产妇并发症之间观察到U形的关联,这表明了最佳的中期生长曲线.
结论:
- 调整混合模型 (SMM) 准确估计母亲体重的潜阶级轨迹.
- 孕产妇体重轨迹是将个体分配到风险组的强有力的指标.
- 适当的孕产妇体重增加对于最大限度地降低妊娠和新生儿不良后果的风险至关重要.
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