在接受ESS治疗的患者中,抗抑郁药,抗焦虑药和ADHD药物的使用率
Alan D Workman1,2, Lillian W Dattilo1,2, Margaret B Mitchell1,2
1Harvard Medical School, Boston, MA.
接受内镜外科手术 (ESS) 的患者使用抗抑郁药和ADHD药物的比率更高. 这表明慢性鼻炎 (CRS) 与需要治疗的心理健康状况之间存在重大联系.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 慢性鼻炎 (CRS) 与较高的精神病并发症率有关.
- 在CRS患者中自我报告的抑郁症可能低估了真正的患病率.
- 药物使用可以作为精神疾病的客观代理.
研究的目的:
- 调查慢性鼻炎 (CRS) 患者精神病并发症的患病率.
- 为了比较CRS患者和匹配的对照组之间的抗抑郁药,抗焦虑药和ADHD药物的使用情况.
- 通过使用药物数据,确定CRS和精神疾病之间的潜在联系.
主要方法:
- 分析了一组2279名接受CRS内镜外科手术 (ESS) 的患者.
- 根据年龄,性别,种族和健康状况,ESS患者与非CRS对照人群进行了1:1匹配.
- 两组之间使用抗抑郁药,抗焦虑药和ADHD药的使用率进行了比较.
主要成果:
- 与对照组 (11.3%) 相比,ESS患者 (22.1%) 的抗抑郁药/抗焦虑药的利用率显著高于对照组 (11.3%) (OR=2.23,P<.001).
- 在ESS患者中,ADHD药物的使用率也明显高 (3.6%) 与对照组 (2.0%) (OR=1.85,P=.001).
- 这些发现表明,在CRS患者中,精神病药物使用的可能性大大增加.
结论:
- 接受内镜外科手术 (ESS) 的患者表现出抗抑郁药物和ADHD药物利用率显著增加.
- 这表明慢性鼻炎 (CRS) 患者群体中精神疾病,如抑郁症和ADHD的潜在患病率更高.
- 客观的药物使用数据支持CRS与精神病并发症之间的关联比以前自我报告更强.
更多相关视频
14:55Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI
Published on: April 18, 2011
05:48The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
Published on: June 12, 2020
相关概念视频
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs
Anxiolytic Drugs: Benzodiazepines and Buspirone
Antidepressant Drugs: MAOIs and Other Agents
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Adrenergic Agonists: Mixed-Action Agents
Ephedrine and pseudoephedrine lack a catecholamine group, making them less susceptible to degradation by metabolic enzymes. They have increased oral bioavailability and lipophilicity, resulting in a longer duration of action. Their response is reduced by...
Sedatives and Hypnotics Drugs: Miscellaneous Agents
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
