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Updated: Jul 28, 2025

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孕妇X受体 (PXR) 缺陷通过激活NRF2/HO-1通路来保护脊髓损伤

Li-Na Xuan1,2, Zhen-Xin Hu3, Zhen-Fu Jiang1,2

  • 1Department of Neurosurgery, the Second Affiliated Hospital of Dalian Medical University, Dalian, China.

CNS neuroscience & therapeutics
|June 3, 2023
PubMed
概括

脊髓损伤 (SCI) 会影响运动功能. 这项研究发现,通过激活NRF2/HO-1通路,抑制Pregnane X受体 (PXR) 改善了恢复,这表明PXR是SCI的治疗标.

关键词:
孕妇X受体 (PXR) 是一个激活方式 激活方式基因淘汰赛 基因淘汰赛氧化应激是一种氧化应激.脊髓损伤 (SCI) 是指脊髓损伤的发生.

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