普罗波对接受胃肠内镜检查的患者的外科手术后睡眠质量的影响:一项前性队列研究
Xiaofei Wu1, Jinhe Deng1, Xiaona Li1
1Department of Anesthesiology, The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong, China.
用于胃肠内镜 (GE) 的普罗波镇静剂暂时恶化了睡眠质量,长达七天. 在接受普罗波镇静剂的患者中,手术后三周睡眠质量恢复正常.
科学领域:
- 胃肠病学 胃肠病学
- 麻醉学 麻醉学
- 睡眠医学 睡眠医学
背景情况:
- 睡眠障碍是胃肠内镜 (GE) 静止后的一些患者报告的副作用.
- 普罗波是一种常用的麻醉剂,用于GE手术期间的镇静.
研究的目的:
- 为了评估普罗波福尔镇静剂对GE后睡眠质量的影响.
- 为了比较经过GE与普罗波镇静治疗的患者的睡眠质量,与没有接受GE的患者进行比较.
主要方法:
- 一项前性队列研究,涉及880名接受GE治疗的患者.
- 患者接受了静脉注射的propofol镇静剂或没有镇静剂 (对照组).
- 在GE之前和之后的不同时间点,使用匹兹堡睡眠质量指数 (PSQI) 和格罗宁根睡眠评分表 (GSQS) 评估睡眠质量.
主要成果:
- 与基线相比,接受普罗波福镇静剂的患者在GE后1天和7天显示GSQS得分 (表明睡眠质量较差) 显著增加.
- 在对照组中没有观察到睡眠质量的显著变化.
- 在GE后3周,在PSQI得分中没有发现群体之间的显著差异.
结论:
- 消化肠道内镜 (GE) 带有普罗波镇静剂,在术后长达七天的时间内,会对睡眠质量产生负面影响.
- 睡眠质量似乎在GE后的三周内恢复,不论是醇镇静剂.
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