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Updated: Jul 28, 2025

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
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抑制SHP2可使各种瘤基因成的固体瘤敏感,以便用向治疗重新治疗

Alexander Drilon1, Manish R Sharma2, Melissa L Johnson3

  • 1Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York.

Cancer discovery
|June 3, 2023
PubMed
概括

SHP2抑制剂PF-07284892与向疗法相结合,可以克服各种癌症的耐药性. 这种组合策略对于以前无法治疗的晚期癌症患者来说是有前途的.

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