恶心,吐和腹在社区获得的急性病毒性呼吸道疾病中很常见
Kira L Newman1, Caitlin R Wolf2, Jennifer K Logue2
1University of Michigan, 3912 Taubman Center, 1500 East Medical Center Drive, SPC 5362, Ann Arbor, MI, 48109-5362, USA. kinewman@med.umich.edu.
Digestive diseases and sciences
|June 3, 2023
概括
胃肠道症状在急性呼吸道疾病 (ARI) 中很常见,影响近30%的病例. 这些症状与疾病严重程度和病原体检测相关,但可能不特定于某些病毒.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 胃肠道 (GI) 症状是已知的急性呼吸道疾病 (ARI) 的并发症,但它们在社区环境中的频率尚未确立.
- 了解ARI中胃肠道症状的患病率和相关性对于有效的诊断和管理至关重要.
研究的目的:
- 为了确定所有年龄段经历社区获得的ARI的个体的胃肠道症状的发生率.
- 调查胃肠道症状与临床结果之间的关联,包括疾病严重程度和病原体检测.
主要方法:
- 在2018-2019冬季期间,西雅图地区的未来社区监视.
- 收集26种呼吸道病原体的聚合酶链反应 (PCR) 测试的中鼻拭子,以及临床和症状数据.
- 使用费舍尔的精确,威尔科克森的等级和值,t测试和多变量逻辑回归来评估胃肠道症状的可能性的统计分析.
主要成果:
- 在3183个ARI发作中,29.4%的人报告了胃肠道症状.
- 胃肠道症状与病原体检测,干扰日常生活,寻求医疗保健和增加症状负担有显著联系.
- 流感,人体甲肺病毒和D68肠道病毒更有可能与胃肠道症状相关,而季节性冠状病毒和鼻病毒的可能性较小.
结论:
- 在社区ARI中经常观察到胃肠道症状,与疾病严重程度和呼吸道病原体的存在相关.
- 这些发现表明,ARI中的胃肠道症状可能是非特异性的,而不是由特定的病原体胃肠道热带性直接介导.
- 对于表现出胃肠道和呼吸系统症状的患者,无论主要的投诉是什么,都建议进行呼吸道病毒检测.
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