相关实验视频

Updated: Jul 28, 2025

Author Spotlight: Investigating Lens Development and Function Through Microinjection of RCAS(A) Retrovirus in Embryonic Chicken Lens

Author Spotlight: Investigating Lens Development and Function Through Microinjection of RCAS(A) Retrovirus in Embryonic Chicken Lens

Published on: September 1, 2023

在中,L-opsin的表达同样通过扩散器和负光透镜减少

Sandra Gisbert¹, Siegfried Wahl¹, Frank Schaeffel²

¹Carl Zeiss Vision International GmbH, Technology, and Innovation, Turnstrasse 27, 73430 Aalen, Germany; Institute for Ophthalmic Research, Eberhard Karls University Tuebingen, Elfriede-Aulhorn-Strasse 7, 72076 Tuebingen, Germany.

Vision research

|June 3, 2023

概括

视网膜L-opsin表达的减少与高空间频率和对比度的损失有关,而不仅仅是光线水平. 这一发现可能表明出血化的一个常见途径.

科学领域:

眼科医生眼科眼科
神经科学是一个神经科学.
视觉科学视觉科学视觉科学

背景情况:

之前的研究表明,使用扩散器的视网膜中L-和M-opsin表达减少.
这种减少的原因尚不清楚,可能是由于改变了空间处理或光衰减.

研究的目的:

调查是否减少了素表达是由于改变了近视发育或光线减少的空间处理.
检查负镜片对视觉表达的影响.

主要方法:

们使用了扩散器或-7D透镜7天.
在对照眼睛中使用中性密度过器匹配视网膜发光度.
使用qRT-PCR量化L-,M-和S-opsin的表达.

主要成果:

与对照眼相比,在扩散剂治疗的眼睛中,L-opsin表达显著降低.
用负光透镜治疗的眼睛中,L-opsin表达也减少了.
结果表明,减少是由于失去高空间频率和对比度,而不是亮度下降.

结论:

减少L-素与空间频率和对比度的减少有关,而不仅仅是光衰减.
在扩散器和负透镜组中类似的L-opsin减少表明了潜在的共同的emetropization路径或减少空间信息的共同影响.

关键词:

肉肉肉肉剥夺近视的近视是一种缺失.双形的双形形可以消极镜头是消极的中性密度过器是中性密度过器.这是一个Opsin表达式.

更多相关视频

Cone-Enriched Cultures from the Retina of Chicken Embryos to Study Rod to Cone Cellular Interactions

Cone-Enriched Cultures from the Retina of Chicken Embryos to Study Rod to Cone Cellular Interactions

Published on: March 20, 2021

Loss-of-Function Approach in the Embryonic Chick Retina by Using Tol2 Transposon-Mediated Transgenic Expression of Artificial microRNAs

Loss-of-Function Approach in the Embryonic Chick Retina by Using Tol2 Transposon-Mediated Transgenic Expression of Artificial microRNAs

Published on: May 18, 2022

相关概念视频

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...