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Updated: Jul 28, 2025

Quantitative Methods to Study Protein Arginine Methyltransferase 1-9 Activity in Cells
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PRMT1甲基化了METTL14以调节其致癌功能

Jingchao Wang1, Zhen Wang1, Hiroyuki Inuzuka1

  • 1Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

Neoplasia (New York, N.Y.)
|June 3, 2023
PubMed
概括

蛋白质氨酸甲基转移酶1 (PRMT1) 甲基化METTL14,这是m6A编写复合物的关键组成部分. 这种氨酸甲基化调节m6A的修饰,并促进细胞增殖,这表明瘤发生的作用.

关键词:
氨酸甲基化的阿尔金因.在METTL14中,使用的是METTL14N6 - 甲基氨酸 (m6A) 的使用.在PRMT1中,

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