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智利低血糖病的修订案例调查议定书:在其他人口中呼吁采取行动
Ramfis Nieto-Martinez1, Jeffrey I Mechanick2, Juan P González-Rivas3
1Precision Care Clinic Corp, Saint Cloud, Florida; Department of Global Health and Population, Harvard TH Chan School of Public Health, Harvard University, Boston, Massachusetts; Foundation for Clinic, Public Health, and Epidemiology Research of Venezuela (FISPEVEN INC), Caracas, Venezuela.
低血糖症,包括糖尿病前期和2型糖尿病,在智利成年人和青少年中很普遍,甚至在正常体重的个人中也有心脏代谢风险因素. 目前的指导方针可能会错过有风险的个体,需要修订查协议.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 心血管疾病的风险风险
背景情况:
- 目前的指导方针建议对超重/肥胖的青少年和成年人进行失糖症查.
- 然而,在一些西班牙裔人群中,肥胖并不总是与失糖症有关.
- 这项研究解决了需要更广泛的失糖症病例发现标准的需求.
研究的目的:
- 为了确定智利人口中的失糖症患病率.
- 评估口服葡萄糖耐受性测试 (OGTT) 的简化标准,独立于BMI和年龄.
- 为心血管疾病风险识别提供经过修订的公共卫生政策信息.
主要方法:
- 来自智利临床中心 (2000-2007年) 的医疗记录的回顾性分析.
- 对至少有一个心脏代谢风险因子 (CMRF) 的患者分析了OGTT数据.
- 对OGTT的标准独立于年龄和体重指数.
主要成果:
- 包括4969名成年人和509名青少年.
- 在这两组中,糖尿病前期的患病率高于2型糖尿病 (T2D).
- 在正常体重的成人和患有CMRF的青少年中发现显著的失糖症 (糖尿病前期和T2D).
结论:
- 支持通过OGTT对失糖症查进行修订的公共卫生政策.
- 建议对6岁以上的个体进行查,至少有一个CMRF,无论体重如何.
- 强调需要重新评估不同人群中心脏代谢风险的病例发现协议.
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