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Updated: Jul 28, 2025

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慢性 Δ9 - 四甲基纳治疗对开放场探索行为和 [3H] SR141716A受体在老鼠大脑中的结合有剂量依赖的影响

Lily Freeman-Striegel1, John Hamilton2, Renuka Kannappan1

  • 1Behavioral Neuropharmacology and Neuroimaging Laboratory on Addictions (BNNLA), Clinical Research Institute on Addictions, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, United States of America.

Life sciences
|June 3, 2023
PubMed
概括

长期高剂量的delta-9-THC (Δ9THC) 暴露在青少年大鼠中降低了大麻素-1受体 (CB1R) 水平和改变了运动活动. 低剂量D9THC在特定的大脑区域增加了CB1R,但没有显著影响活动.

关键词:
吸毒成 吸毒成 是一种成.无线电自动图像 - 无线电自动图像CB1 CB1 CB1 的意思是什么意思.大麻大麻大麻大麻大麻大麻大麻类阿片类药物 类阿片类药物Δ9-四化大麻醇 (Tetrahydrocannabinol) 是一种多化大麻的化合物.

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CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
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