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强大的IL-2-依赖性抗瘤免疫疗法需要针对瘤特异性CD8的高亲和度IL-2R

Kathryn M LaPorte1, Rosmely Hernandez1, Alicia Santos Savio1

  • 1Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, USA.

Journal for immunotherapy of cancer
|June 3, 2023
PubMed
概括

用高剂量的小鼠IL-2/CD25准高亲和度IL-2受体可促进强大的抗瘤免疫和记忆反应,特别是与PD-1阻断相结合,可增强癌症治疗.

关键词:
有CD8阳性的T淋巴细胞.细胞因子 细胞因子免疫检查点抑制剂 免疫检查点抑制剂免疫疗法 免疫疗法瘤微环境是一个微环境.

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