在转移性细胞癌中脑转移的管理
Elshad Hasanov1, Eric Jonasch2
1Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, 1400 Holcombe Boulevard FC11.3055, Houston, TX 77030, USA.
Hematology/oncology clinics of North America
|June 3, 2023
概括
大脑转移是细胞癌的不良预后指标. 监测和放射治疗等治疗对于控制内疾病至关重要.
科学领域:
- 在瘤学瘤学.
- 神经外科 神经外科
- 辐射疗法 辐射疗法
背景情况:
- 大脑转移显著恶化细胞癌 (RCC) 患者的预后.
- 在RCC治疗期间,定期监测中枢神经系统 (CNS) 是必不可少的.
研究的目的:
- 总结目前在细胞癌中管理大脑转移的方法.
- 突出目前正在进行的研究,研究中枢神经系统疾病的新型全身疗法.
主要方法:
- 对大脑转移的标准治疗方法的审查.
- 讨论临床研究中的新兴治疗策略.
主要成果:
- 立体辐射手术,全脑辐射疗法和手术切除是已知的治疗方法.
- 向治疗和免疫检查点抑制剂正在中枢神经系统转移的临床试验中进行评估.
结论:
- 在RCC中进行脑转移的有效管理需要采用多模式的方法.
- 试验性疗法有望改善内RCC进展患者的治疗结果.
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