Kratom 的长期健康影响 (
Darika Saingam1, Darshan Singh2, Alan F Geater1
1Department of Epidemiology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Substance use & misuse
|June 3, 2023
概括
在泰国长期使用克拉并没有增加常见的健康问题,但存在药物依赖的风险. 严重的依赖与强烈的戒断症状有关,尽管没有记录死亡.
科学领域:
- 民族植物学 民族植物学
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 在泰国,Mitragyna speciosa (Kratom) 有传统的药用.
- 有限的研究存在于 Kratom 的长期健康影响.
- 这项研究调查了在泰国南部使用克拉对健康的长期影响.
研究的目的:
- 为了检查 Kratom 消费对健康的长期影响.
- 评估Kratom使用模式和健康结果之间的关系.
- 为了确定与定期使用Kratom相关的潜在风险.
主要方法:
- 2011-2015年在泰国南部进行的基于社区的调查.
- 招募了1118名25岁以上的男性受访者 (常规用户,偶尔用户,前用户,非用户).
- 在多个调查波中对受访者进行跟踪,以追踪健康状况和使用模式.
主要成果:
- 与非使用者相比,Kratom使用者报告说,常见的健康投诉没有增加.
- 常规的Kratom用户更有可能报告成和经历中毒效应.
- 具有较高Kratom依赖度的个体经历了更强烈的戒断症状.
结论:
- 定期长期克拉叶与增加的常见健康问题无关,但会带来药物依赖的风险.
- 严重的Kratom依赖与强烈的戒断症状有关.
- 虽然没有死因归因于传统的Kratom使用,但同时吸烟 (烟草/香烟) 在用户中是一个重大问题.
相关概念视频
Stress and Mental Health
188
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
188
Stress Prevention and Stress Management Techniques IV
50
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
50
Stimulants
254
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
254
Substance Use Disorders Affecting Sleep
199
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
199
Chronic Kidney Disease II: Clinical Manifestations
46
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
46
Desensitization and Tachyphylaxis
1.9K
Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
1.9K


